Protocol for a systematic review of living labs in healthcare

Protocol for a systematic review of living labs in healthcare

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Healthcare is more and more challenged to satisfy the calls for of consumer involvement and data mobilisation required by the 21st-century patient-centred and knowledge-based economies. Innovations are wanted to scale back problematic limitations to data alternate and enhance collaborative downside fixing. Living labs, as open data techniques, have the potential to handle these gaps however are underexplored in healthcare.  We will conduct the primary systematic review of living labs throughout healthcare contexts. We will comprehensively search the next on-line databases from inception to 31 December 2020:
Scopus, the Cochrane Library (Wiley), Medline (OVID), Embase (OVID), Web of Science, PsycINFO (OVID) and EBSCOhost databases together with Academic Search Complete, Business Source Premier, Canadian Reference Centre, CINAHL, MasterFILE Premier, SPORTDiscus, Library & Information Science Source, Library, Information Science & Technology Abstracts, AgeLine, EconLit, Art Full Text, Women’s Studies International and Social Work Abstracts. We will search for gray literature utilizing Google superior methods and books/e book chapters by way of scholarly and bibliographical databases. We will use a dual-reviewer, two-step choice course of with pre-established inclusion standards and restrict to English language publications.
Empirical research of any design inspecting living lab improvement, implementation or analysis in well being or healthcare can be included. We will use the Mixed Methods Appraisal Tool (MMAT) for methodological high quality appraisal and Covidence software program for review administration, and we are going to extract information on pre-established variables equivalent to lab context and technological platforms. We will create proof tables and analyse throughout variables equivalent to focal intention and achievement of living lab ideas, such because the use of cocreation and multimethod approaches.
We will tabulate information for descriptive reporting and narrative synthesis to establish present functions, approaches and promising areas for living lab improvement throughout well being contexts.  Ethical approval was not required for this review. This review will inform analysis into living labs in well being environments, together with steering for a living lab in paediatric rehabilitation. Academic publications shared by way of collaborative networks and social media channels will present substantive data to the rising tech-health improvement sector and to researchers, practitioners and organisations looking for enhanced affected person/stakeholder engagement and improvements in data translation and evidence-based follow.

Aerosol-jet printing facilitates the speedy prototyping of microfluidic units with versatile geometries and exact channel functionalization

Microfluidics has emerged as a highly effective analytical device for biology and biomedical analysis, with makes use of starting from single-cell phenotyping to drug discovery and medical diagnostics, and solely small pattern volumes required for testing. The skill to quickly prototype new designs is vastly useful in a analysis atmosphere, however the excessive value, sluggish turnaround, and wasteful nature of generally used fabrication methods, notably for complicated multi-layer geometries, severely impede the event course of. In addition, microfluidic channels in most units presently play a passive function and are sometimes used to direct flows.

This would contain incorporating useful supplies straight inside the channels that may partake in, information or facilitate reactions in exactly managed microenvironments. Here we show the use of Aerosol Jet Printing (AJP) to quickly produce bespoke molds for microfluidic units with a vary of totally different geometries and exact “in-channel” functionalization. We present that such a sophisticated microscale additive manufacturing technique can be utilized to quickly design cost-efficient and customised microfluidic units, with the power so as to add useful coatings at particular places inside the microfluidic channels.

We show the functionalization capabilities of our method by particularly coating a part of a microfluidic channel with polyvinyl alcohol to render it hydrophilic. This versatile microfluidic gadget prototyping method can be a highly effective assist for organic and bio-medical analysis in each educational and industrial contexts. The skill to “functionalize” the channels with totally different supplies in exact spatial places could be a main benefit for a vary of functions.

Protocol for a systematic review of living labs in healthcare

Renting Valuable Assets: Knowledge and Value Production in Academic Science

This paper explores what it takes for analysis laboratories to supply priceless data in educational establishments marked by the coexistence of a number of evaluative frameworks. Drawing upon ethnographic fieldwork carried out in two UK-based epigenetics analysis laboratories, I study the set of practices by way of which analysis teams intertwine data manufacturing with the making of scientific, well being and wealth worth. This contains constructing and sustaining a portfolio of priceless assets, equivalent to experience, scientific credibility or information and turning these assets into property by rigorously organising and managing their worth. Laboratories then put these property to productive use inside and out of doors their labs in the direction of the creation or extraction of worth.

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I establish two fashions for producing worth inside educational science: a commodity-based mannequin whereby laboratories mobilise their property to supply outcomes, which may be transformed into publications for the buildup of credibility capital; and a rentier mannequin of accumulation, whereby laboratories personal priceless property, which they hire out to others exterior their lab towards a income. Following current developments in STS on worth manufacturing in the bioeconomy, I argue that the ideas of asset and hire are important analytical instruments to become familiar with the origins of worth inside educational science.